A New Lignan from Fruit of Schisandra wilsoniana A.C.Smith and its Anti-HIV activity

Yi-Ping Fan; Li-Ping Duan; Xiu-Hua Dong; Yun Dai; Gan-Peng Li

Issue

Vol. 21 No. 7 (2009): Vol 21 Issue 7

Issue Published : May 5, 2009

A New Lignan from Fruit of Schisandra wilsoniana A.C.Smith and its Anti-HIV activity

Yi-Ping Fan

Department of Chemistry, Yuxi Teacher's College, Yuxi 653100, P.R. China.

Li-Ping Duan

Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China

Xiu-Hua Dong

Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China

Yun Dai

Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China

Gan-Peng Li

Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China

Corresponding Author(s) : Gan-Peng Li

ganpeng_li@sina.com; huqiufena@yahoo.com.cn

Asian Journal of Chemistry, Vol. 21 No. 7 (2009): Vol 21 Issue 7
Article Published : March 30, 2010

Abstract

A new lignan, willignan A, was isolated from the fruit of Schisandra wilsoniana A.C.Smith. It structures and stereochemistry was elucidated by analysis of spectroscopic data. This compound was evaluated for its inhibitory activity against HIV-1 and it shows an anti-HIV activity with EC₅₀ (median effect concentration) value of 12.5 μg/mL and a Therapeutic Index (TI) above 16.00.

Keywords

Lignan Willignan A Schisandra wilsoniana A.C.Smith Anti-HIV-1 activity

Fan, Y.-P., Duan, L.-P., Dong, X.-H., Dai, Y., & Li, G.-P. (2010). A New Lignan from Fruit of Schisandra wilsoniana A.C.Smith and its Anti-HIV activity. Asian Journal of Chemistry, 21(7), 5488–5492. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/18342

Issue

Vol. 21 No. 7 (2009): Vol 21 Issue 7

A New Lignan from Fruit of Schisandra wilsoniana A.C.Smith and its Anti-HIV activity

Corresponding Author(s) : Gan-Peng Li

Abstract

Keywords

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