Issue

Vol. 21 No. 7 (2009): Vol 21 Issue 7

A New Lignan from Fruit of Schisandra wilsoniana A.C.Smith and its Anti-HIV activity

Yi-Ping Fan
Department of Chemistry, Yuxi Teacher's College, Yuxi 653100, P.R. China.
Li-Ping Duan
Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China
Xiu-Hua Dong
Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China
Yun Dai
Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China
Gan-Peng Li
Department of Chemistry, Yunnan Nationalities University, Kunming 650031, P.R. China

Corresponding Author(s) : Gan-Peng Li

ganpeng_li@sina.com; huqiufena@yahoo.com.cn

Asian Journal of Chemistry, Vol. 21 No. 7 (2009): Vol 21 Issue 7

Abstract

A new lignan, willignan A, was isolated from the fruit of Schisandra wilsoniana A.C.Smith. It structures and stereochemistry was elucidated by analysis of spectroscopic data. This compound was evaluated for its inhibitory activity against HIV-1 and it shows an anti-HIV activity with EC50 (median effect concentration) value of 12.5 μg/mL and a Therapeutic Index (TI) above 16.00.

Keywords

Lignan Willignan A Schisandra wilsoniana A.C.Smith Anti-HIV-1 activity
(1)
Fan, Y.-P.; Duan, L.-P.; Dong, X.-H.; Dai, Y.; Li, G.-P. A New Lignan from Fruit of Schisandra Wilsoniana A.C.Smith and Its Anti-HIV Activity. ajc 2010, 21, 5488-5492.
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 23 Download : 41