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Green Synthesis, Characterization of Zinc Oxide Nanoparticles and their Incorporation into Glass Ionomer Cement for Inhibition of Streptococcus mutans
Corresponding Author(s) : P. Dhamodhar
Asian Journal of Chemistry,
Vol. 33 No. 3 (2021): Vol 33 Issue 3
Abstract
In present study, zinc oxide nanoparticles were synthesised using Syzygium aromaticum and characterized using UV visible spectroscopy, SEM, XRD and FTIR techniques. The characteristic hexagonal structure of the ZnO nanoparticles was confirmed through XRD analysis. The UV-Visible spectrum showed a strong absorbance at 366 nm confirming the presence of ZnO and the peak at 496 cm-1 in FTIR indicated the Zn-O stretch bond. Average size of the zinc oxide nanoparticles obtained from SEM analysis was found to be 86 nm. The zinc oxide nanoparticles exhibited better antibacterial activity than clove extract, when tested against clinical isolates of Streptococcus mutans. The nanoparticles incorporated into the dental restorative material, glass ionomer cement (GIC) were tested against S. mutans and exhibited better antibacterial activity than clove extract. Glass ionomer cement (GIC) did not exhibit antibacterial activity alone, but the incorporation of ZnO nanoparticles into GIC significantly improved antibacterial activity. Hence, ZnO embedded GIC is a promising material in restorative dentistry for preventing the recurrence of dental caries.
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- M. Calisir, eds.: A.B. Tekinay, Nanomaterials for Regenerative Medicine, Stem Cell Biology and Regenerative Medicine, Humana, Cham., Chap. 7 (2019).
- G.H.W. Bowden, Microb. Ecol. Health Dis., 12, 138 (2000); https://doi.org/10.1080/089106000750051819
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- P. Dhamodhar, S. Murthy, Channarayappa, S.S. Shantha Kumar and H.N. Indiresha, Int. J. Pharma Bio Sci., 5, 122 (2014).
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- K. Chaieb, H. Hajlaoui, T. Zmantar, A.B. Kahla-Nakbi, M. Rouabhia, K. Mahdouani and A. Bakhrouf, Phytother. Res., 21, 501 (2007); https://doi.org/10.1002/ptr.2124
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- K.S. Siddiqi, A. Rahman, Tajuddin and A. Husen, Nanoscale Res. Lett., 13, 141 (2018); https://doi.org/10.1186/s11671-018-2532-3
- N. Niño-Martínez, M.F. Salas Orozco, G.-A. Martínez-Castañón, F. Torres Méndez and F. Ruiz, Int. J. Mol. Sci., 20, 2808 (2019); https://doi.org/10.3390/ijms20112808
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References
M. Calisir, eds.: A.B. Tekinay, Nanomaterials for Regenerative Medicine, Stem Cell Biology and Regenerative Medicine, Humana, Cham., Chap. 7 (2019).
G.H.W. Bowden, Microb. Ecol. Health Dis., 12, 138 (2000); https://doi.org/10.1080/089106000750051819
M.E. Curzon and A.J. Preston, Caries Res., 38, 24 (2004); https://doi.org/10.1159/000074359
E.D.B. Aguilar, L.K. Barker, M.T. Canto, B.A. Dye, B.F. Gooch, S.O. Griffin, J. Hyman, F. Jaramillo, A. Kingman, R.N. Raymer, R.H. Selwitz and T. Wu, MMWR Surveill. Summ., 54, 1 (2005).
P.E. Petersen and T. Yamamoto, Community Dent. Oral Epidemiol., 33, 81 (2005); https://doi.org/10.1111/j.1600-0528.2004.00219.x
A.M. Maru and S. Narendran, J. Contemp. Dent. Pract., 13, 382 (2012); https://doi.org/10.5005/jp-journals-10024-1155
P. Dhamodhar, S. Murthy, Channarayappa, S.S. Shantha Kumar and H.N. Indiresha, Int. J. Pharma Bio Sci., 5, 122 (2014).
S.R. Thakur, A. Thomas and S.B. Shetty, J. Indian Soc. Pedod. Prev. Dent., 34, 65 (2016); https://doi.org/10.4103/0970-4388.175518
M. El-Salhy, E. Soderling, E. Honkala, M. Fontana, S. Flannagan, A. Kokaras, B.J. Paster, A. Varghese and S. Honkala, Eur. J. Paediatr. Dent., 17, 188 (2016).
P.E. Petersen, Community Dent. Oral Epidemiol., 31, 3 (2003); https://doi.org/10.1046/j..2003.com122.x
A.F. Zandoná, E. Santiago, G.J. Eckert, B.P. Katz, S.P. de Oliveira, O.R. Capin, M. Mau and D.T. Zero, J. Dent. Res., 91, 841 (2012); https://doi.org/10.1177/0022034512455030
B. Kouidhi, Y.M. Al Qurashi and K. Chaieb, Microb. Pathog., 80, 39 (2015); https://doi.org/10.1016/j.micpath.2015.02.007
G.N. Karibasappa and A. Sujatha, IOSR J. Dent. Med. Sci., 13, 112 (2014).
S. Godreuil, N. Leban, A. Padilla, R. Hamel, N. Luplertlop, A. Chauffour, M. Vittecoq, F. Hoh, F. Thomas, W. Sougakoff, C. Lionne, H. Yssel and D. Misse, PLoS One, 9, e105441 (2014); https://doi.org/10.1371/journal.pone.0105441
Y. Liao, J. Chen, B.W. Brandt, Y. Zhu, J. Li, C. van Loveren and D.M. Deng, PLoS One, 10, e0122630 (2015); https://doi.org/10.1371/journal.pone.0122630
M.J. Hajipour, K.M. Fromm, A. Akbar Ashkarran, D. Jimenez de Aberasturi, I.R. Larramendi, T. Rojo, V. Serpooshan, W.J. Parak and M. Mahmoudi, Trends Biotechnol., 30, 499 (2012); https://doi.org/10.1016/j.tibtech.2012.06.004
H.J. Park, S. Park, J. Roh, S. Kim, K. Choi, J. Yi, Y. Kim and J. Yoon, J. Ind. Eng. Chem., 19, 614 (2013); https://doi.org/10.1016/j.jiec.2012.09.013
R. Kalaiarasi, N. Jayalakshmi and P. Venkatachalam, Plant Cell Biotechnol. Mol. Biol., 11, 1 (2010).
K. Chaieb, H. Hajlaoui, T. Zmantar, A.B. Kahla-Nakbi, M. Rouabhia, K. Mahdouani and A. Bakhrouf, Phytother. Res., 21, 501 (2007); https://doi.org/10.1002/ptr.2124
D. Ray, S. Sinha, S. Saha, S. Karmakar, R.N. Dutta, S. Bhattacharya, N.K. Pal and B. Bhattacharya, Al-Ameen J. Med. Sci., 3, 146 (2010).
C. Chena, B. Yu, P. Liu, J.F. Liu and L. Wang, J. Ceram. Process. Res., 12, 420 (2011).
S.Y. Pung, W.P. Lee and A. Aziz, Int. J. Inorg. Chem., 2012, 1 (2012); https://doi.org/10.1155/2012/608183
P. Kumbhakar, D. Singh, C.S. Tiwary and A.K. Mitra, Chalcogenide Lett., 5, 387 (2008).
A.J. Reddy, M.K. Kokila, H. Nagabhushana, R.P.S. Chakradhar, C. Shivakumara, J.L. Rao and B.M. Nagabhushana, J. Alloys Compd., 509, 5349 (2011); https://doi.org/10.1016/j.jallcom.2011.02.043
Y. Jeong, D.W. Lim and J. Choi, Adv. Mater. Sci. Eng., 2014, 1 (2014); https://doi.org/10.1155/2014/763807
K.S. Siddiqi, A. Rahman, Tajuddin and A. Husen, Nanoscale Res. Lett., 13, 141 (2018); https://doi.org/10.1186/s11671-018-2532-3
N. Niño-Martínez, M.F. Salas Orozco, G.-A. Martínez-Castañón, F. Torres Méndez and F. Ruiz, Int. J. Mol. Sci., 20, 2808 (2019); https://doi.org/10.3390/ijms20112808
Z. Jowkar, M. Jowkar and F. Shafiei, J. Clin. Exp. Dent., 11, e275 (2019); https://doi.org/10.4317/jced.55522
L. Paiva, T.K.S. Fidalgo, L.P. da Costa, L.C. Maia, L. Balan, K. Anselme, L. Ploux and R.M.S.M. Thire, J. Dent., 69, 102 (2018); https://doi.org/10.1016/j.jdent.2017.12.003