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Vol. 30 No. 7 (2018): Vol 30 Issue 7

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Synthesis, Spectroscopic Studies, Biological Screening and Geometrical Optimization of Bidentate Schiff's Base Ligand and their Mn(II) and Co(II) Complexes

https://doi.org/10.14233/ajchem.2018.21347
Pallavi Jain
Department of Chemistry, SRM Institute of Science & Technology, Modinagar-201 204, India
Dinesh Kumar
School of Chemical Sciences, Central University of Gujarat, Gandhinagar-382 030, India
Sulekh Chandra
Department of Chemistry, Zakir Hussain Delhi College, J.L.N. Marg, New Delhi-110 002, India

Corresponding Author(s) : Pallavi Jain

palli24@gmail.com

Asian Journal of Chemistry, Vol. 30 No. 7 (2018): Vol 30 Issue 7

Abstract

A series of Mn(II) and Co(II) complexes were obtained after the condensation of ligand methylcarbamatesemicarbazone (L) and corresponding metal salt. The ratio of metal salt to ligand was 1:2. The conventional condensation reaction was employed to synthesize the multidonor ligand by refluxing methylcarbamate and semicarbazide in 1:1 ratio. The mode of bonding and geometry of the synthesized complexes was confirmed by elemental analysis, magnetic susceptibility, molar conductance, IR, 1H NMR, Mass, electronic spectra, EPR and molecular modeling. The general composition ML2X2 was assigned to transition metal complexes, where M = Mn(II) and Co(II), L = methylcarbamatesemicarbazone and X = CH3COO–, NO3 –, The non-electrolytic nature of metal complexes was confirmed by molar conductance values with composition [ML2X2]. The spectral studies suggested six coordinated geometry for the synthesized complexes. Molecular Modeling of ligand and complexes was also done by using Gaussian. The biological activities of all the synthesized compounds were also evaluated against two different bacterias. Based on antimicrobial results, it was concluded that metal complexes exhibited higher inhibition potential than free Schiff’s base ligand.

Keywords

Schiff’s base ligand Metal complexes Spectroscopic Molecular Modeling Antimicrobial study
Jain, P., Kumar, D., & Chandra, S. (2018). Synthesis, Spectroscopic Studies, Biological Screening and Geometrical Optimization of Bidentate Schiff’s Base Ligand and their Mn(II) and Co(II) Complexes. Asian Journal of Chemistry, 30(7), 1664–1670. https://doi.org/10.14233/ajchem.2018.21347
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