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Synthesis, Characterization and Biocidal Properties of Some Random Copolyesters Containing Chalcone Diol Moiety
Corresponding Author(s) : Mohd Imran Rais
Asian Journal of Chemistry,
Vol. 30 No. 7 (2018): Vol 30 Issue 7
Abstract
A series of 8 random copolyesters were produced by polycondensation of chalcone diol with terepththaloyl chloride, isophthaloyl chloride, adipoyl chloride, oxalyl chloride, glutaryl chloride and succinyl chloride. The Claisen-Schmidt reaction in acidic medium was used to prepare chalcone diol. The characterization of prepard random copolyesters was done by checking the solubility in different solvents and viscosity measurements. FT-IR, 1H- and 13C-NMR spectroscopic techniques were applied to study the structure of repeating units available in the polymer chain. Thermal analysis was done by DSC. The well-diffusion method was employed to establish the biocidal efficacy of these 8 copolyesters by using a Gram-positive and Gram-negative bacteria.
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References
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D.K. Mahapatra, S.K. Bharti and V. Asati, Eur. J. Med. Chem., 101, 496 (2015); https://doi.org/10.1016/j.ejmech.2015.06.052.
Y.K. Srivastava, Rasayan J. Chem., 1, 884 (2008).
M.N. Gomes, E.N. Muratov, M. Pereira, J.C. Peixoto, L.P. Rosseto, P.V.L. Cravo, C.H. Andrade and B.J. Neves, Molecules, 22, 1210 (2017); https://doi.org/10.3390/molecules22081210.
K. Patel, C. Karthikeyan, V.R. Solomon, N.S.H.N. Moorthy, H. Lee, K. Sahu, G.S. Deora and P. Trivedi, Lett. Drugs Design Discov., 8, 308 (2011); https://doi.org/10.2174/157018011794839475.
M.L. Go, X. Wu and X.L. Liu, Curr. Med. Chem., 12, 483 (2005); https://doi.org/10.2174/0929867053363153.
F. Chimenti, R. Fioravanti, A. Bolasco, P. Chimenti, D. Secci, F. Rossi, M. Yáñez, F. Orallo, F. Ortuso and S. Alcaro, J. Med. Chem., 52, 2818 (2009); https://doi.org/10.1021/jm801590u.
M. Liu, P. Wilairat and M.L. Go, J. Med. Chem., 44, 4443 (2001); https://doi.org/10.1021/jm0101747.
S. Ducki, R. Forrest, J.A. Hadfield, A. Kendall, N.J. Lawrence, A.T. McGown and D. Rennison, Bioorg. Med. Chem. Lett., 8, 1051 (1998); https://doi.org/10.1016/S0960-894X(98)00162-0.
F. Bois, A. Boumendjel, A.-M. Mariotte, G. Conseil and A. Di Petro, Bioorg. Med. Chem., 7, 2691 (1999); https://doi.org/10.1016/S0968-0896(99)00218-7.
J.R. Dimmock, D.W. Elias, M.A. Beazely and N.M. Kandepu, Curr. Med. Chem., 6, 1125 (1999).
N. Heidarzadeh, M. Rafizadeh, F.A. Taromi, J. Puiggalí, L.J. Del Valle and L. Franco, J. Polym. Res., 24, 163 (2012); https://doi.org/10.1007/s10965-017-1318-0.
M. Wojtczak, S. Dutkiewicz, A. Galeski and A. Gutowska, Polymer, 113, 119 (2017); https://doi.org/10.1016/j.polymer.2017.02.054.
T.S. Perundevi, D.R. Jonathan and S. Kothai, J. Chem. Chem. Sci., 6, 329 (2016).
J. Sidharthan and T. Peter Amaladhas, J. Polym. Res., 24, 53 (2017); https://doi.org/10.1007/s10965-017-1206-7.
R.S. Samuel, D.R. Jonathan, Y. Christurajan, S. Jayakumar and R. Pichai, Indian J. Sci. Technol., 3, 696 (2010).
M. Chitra, T.V. Rajendran, V. Duraipandiyan, Y.C. Rajan and D.R. Jonathan and Indian J. Sci. Technol., 3, 890 (2010).
M.R. Hibbs, M. Vargas, J. Holtzclaw, W. Rich, D.M. Collard and D.A. Schiraldi, Macromolecules, 36, 7543 (2003); https://doi.org/10.1021/ma034425s.
R.S. Selvi, R. Nanthini and G. Sukanyaa, J. Chem. Pharm. Res., 4, 393 (2012).
K.A. Nandekar, J.R. Dontulwar and W.B. Gurnule, J. Chem. Pharm. Res., 4, 3638 (2012).
N. Malathi and D.R. Singh, Indian J. Sci. Technol., 5, 2302 (2012).
Y.C. Rajan, C.C. Kanakam, S.P. Selvam and K. Murugesan, Tetrahedron Lett., 48, 8562 (2007); https://doi.org/10.1016/j.tetlet.2007.09.097.
S.J. Francis, D.R. Jonathan and D.R. Singh, J. Chem. Pharm. Res., 6, 1155 (2014).
M.K. Sukanya, S. Suku and S.R. Aruna, Int. J. Pharma. Bio. Sci., 4, 55 (2013).