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Phytochemicals from Calophyllum depressinervosum
Corresponding Author(s) : G.C.L. Ee
Asian Journal of Chemistry,
Vol. 30 No. 5 (2018): Vol 30 Issue 5, 2018
Abstract
A phytochemical investigation on the stem bark of Calophyllum depressinervosum resulted in the isolation of four xanthones, one coumarin and one kavalactone which were elucidated to be caloxanthone B (1), caloxanthone I (2), caloxanthone J (3), xanthochymone B (4), calopolynolide B (5) and desmethoxyyangonim (6). The structures of the compounds were elucidated using spectroscopic analysis such as 1D and 2D NMR together with MS technique. The dichloromethane extract of Calophyllum depressinervosum gave good cell viability on RAW246.7 cells for potential antiinflammatory test with an IC50 value of 17.19 ± 0.007 μg/mL.
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- V. Cechinel Filho, C. Meyre-Silva and R. Niero, Chem. Biodivers., 6, 313 (2009); https://doi.org/10.1002/cbdv.200800082.
- Tree Flora of Malays: A Manual for Foresters, Longman Group Limited, London, vol. 2 (1973).
- G.C.L. Ee, S.H. Mah, M. Rahmani, Y.H. Taufiq-Yap, S.S. Teh and Y.M. Lim, J. Asian Nat. Prod. Res., 13, 956 (2011); https://doi.org/10.1080/10286020.2011.600248.
- S.H. Mah, G.C.L. Ee, S.S. Teh, M. Rahmani, Y.M. Lim and R. Go, Molecules, 17, 8303 (2012); https://doi.org/10.3390/molecules17078303.
- X.H. Su, M.L. Zhang, L.G. Li, C.H. Huo, Y.C. Gu and Q.W. Shi, Chem. Biodivers., 5, 2579 (2008); https://doi.org/10.1002/cbdv.200890215.
- G.Y. Chen, G.Y. Zhu, C.R. Han, J. Zhao, X.P. Song and W.F. Fong, ARKIVOC, 249 (2008); https://doi.org/10.3998/ark.5550190.0009.d27.
- M. Iinuma, H. Tosa, T. Tanaka and S. Yonemori, Phytochemistry, 35, 527 (1994); https://doi.org/10.1016/S0031-9422(00)94795-2.
- H. Ranjith W. Dharmaratne, N.P. Dhammika Nanayakkara and I.A. Khan, Phytochemistry, 59, 429 (2002); https://doi.org/10.1016/S0031-9422(01)00443-5.
- K. Trisuwan, S. Boonyaketgoson, V. Rukachaisirikul and S. Phongpaichit, Tetrahedron Lett., 55, 3600 (2014); https://doi.org/10.1016/j.tetlet.2014.04.105.
- J.J. Chen, M. Xu, S.D. Lou, H.Y. Wang and J.C. Xu, Acta botan. Yunnanica, 23, 521 (2001)
References
V. Cechinel Filho, C. Meyre-Silva and R. Niero, Chem. Biodivers., 6, 313 (2009); https://doi.org/10.1002/cbdv.200800082.
Tree Flora of Malays: A Manual for Foresters, Longman Group Limited, London, vol. 2 (1973).
G.C.L. Ee, S.H. Mah, M. Rahmani, Y.H. Taufiq-Yap, S.S. Teh and Y.M. Lim, J. Asian Nat. Prod. Res., 13, 956 (2011); https://doi.org/10.1080/10286020.2011.600248.
S.H. Mah, G.C.L. Ee, S.S. Teh, M. Rahmani, Y.M. Lim and R. Go, Molecules, 17, 8303 (2012); https://doi.org/10.3390/molecules17078303.
X.H. Su, M.L. Zhang, L.G. Li, C.H. Huo, Y.C. Gu and Q.W. Shi, Chem. Biodivers., 5, 2579 (2008); https://doi.org/10.1002/cbdv.200890215.
G.Y. Chen, G.Y. Zhu, C.R. Han, J. Zhao, X.P. Song and W.F. Fong, ARKIVOC, 249 (2008); https://doi.org/10.3998/ark.5550190.0009.d27.
M. Iinuma, H. Tosa, T. Tanaka and S. Yonemori, Phytochemistry, 35, 527 (1994); https://doi.org/10.1016/S0031-9422(00)94795-2.
H. Ranjith W. Dharmaratne, N.P. Dhammika Nanayakkara and I.A. Khan, Phytochemistry, 59, 429 (2002); https://doi.org/10.1016/S0031-9422(01)00443-5.
K. Trisuwan, S. Boonyaketgoson, V. Rukachaisirikul and S. Phongpaichit, Tetrahedron Lett., 55, 3600 (2014); https://doi.org/10.1016/j.tetlet.2014.04.105.
J.J. Chen, M. Xu, S.D. Lou, H.Y. Wang and J.C. Xu, Acta botan. Yunnanica, 23, 521 (2001)