High Temperature Synthesis and Characterization of Hydroxyapatite Doped with Silver Nanoparticles

Abstract

Calcium hydroxyapatite, is a material which is closely resembles

with bone apatite and exhibits excellent osteoconductivity. In this work,

the synthesis of hydroxyapatite in a modified synthetic body fluid (SBF)

solutions at 37 °C and pH of 7.4 was performed using novel chemical

precipitation technique. Then after heat operation at 1200 ºC, on filtered

precipitated result calcium hydroxyapatite were produced. Hydroxyapatite

doped with silver nanoparticles was prepared by treatment with

AgNO₃ solution and reduction of Ag⁺ ions by sodium borohydrate

solution. The formations of the silver nanoparticles on the calcium hydroxyapatite

structure were confirmed by X-ray diffraction and transmission

electron microscopy. Transmission electron microscopy image shows

the nanostructure of silver particles, being formed on hydroxyapatite

texture.