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Effects of High-Rate Frequency Modulation Treatment on Malondialdehyde in Diabetic Polyneuropathy
Asian Journal of Chemistry,
Vol. 22 No. 1 (2010): Vol 22 Issue 1, 2010
Abstract
This study is planned to investigate the effects of transcutaneous
electrical nerve stimulation (TENS) treatment on patients which have
diabetic polyneuropathy. Fourteen diabetic polyneuropathy patients suffering
ischemic pain were examined during the cure. Malondialdehyde (MDA)
and glycemia levels were determined by collecting 5 mL blood samples
from 14 patients 24 h before beginning the treatment. In case 50 Hz
signals as high-rate frequency modulation (HRFM; continuous pulses
changed from 90 Hz to 55 Hz over 90 msec, 1.3 times a second), were
applied to patients as long as 20 d for 20 min a day. Transcutaneous
electrical nerve stimulation (TENS) treatment increased significantly
free oxygen radicals (p < 0.05). The levels of MDA before TENS were
compared to the levels of MDA after TENS and the end of the following
term of 20 days by paired sample test and a meaningful increase was
seen significantly (p < 0.01). Besides, glycemia levels were decreased
significantly before TENS-after TENS treatment (p < 0.01) and not
changed before TENS and the end of the following term of 20 d (p > 0.05).
Moreover, it was observed that MDA levels were decreased significantly
between in the final of the treatment and the end of the following
term of 20 d (p < 0.01). Glycemia levels were not changed significantly
after TENS and the end of the following term of 20 d (p > 0.05). According
to this results, it is observed that TENS treatment has been positive
effect on polyneuropathy.
electrical nerve stimulation (TENS) treatment on patients which have
diabetic polyneuropathy. Fourteen diabetic polyneuropathy patients suffering
ischemic pain were examined during the cure. Malondialdehyde (MDA)
and glycemia levels were determined by collecting 5 mL blood samples
from 14 patients 24 h before beginning the treatment. In case 50 Hz
signals as high-rate frequency modulation (HRFM; continuous pulses
changed from 90 Hz to 55 Hz over 90 msec, 1.3 times a second), were
applied to patients as long as 20 d for 20 min a day. Transcutaneous
electrical nerve stimulation (TENS) treatment increased significantly
free oxygen radicals (p < 0.05). The levels of MDA before TENS were
compared to the levels of MDA after TENS and the end of the following
term of 20 days by paired sample test and a meaningful increase was
seen significantly (p < 0.01). Besides, glycemia levels were decreased
significantly before TENS-after TENS treatment (p < 0.01) and not
changed before TENS and the end of the following term of 20 d (p > 0.05).
Moreover, it was observed that MDA levels were decreased significantly
between in the final of the treatment and the end of the following
term of 20 d (p < 0.01). Glycemia levels were not changed significantly
after TENS and the end of the following term of 20 d (p > 0.05). According
to this results, it is observed that TENS treatment has been positive
effect on polyneuropathy.
Keywords
Diabetes
Polyneuropathy
Transcutaneous electrical nerve stimulation
Malondialdehyde.
KAVAK*, S., DULGER†, H., TULGAR‡, M., & ALKIS§, I. (2009). Effects of High-Rate Frequency Modulation Treatment on Malondialdehyde in Diabetic Polyneuropathy. Asian Journal of Chemistry, 22(1), 633–640. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/16687
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