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Efficient P2O5 Catalyzed Microwave Assisted One Pot Synthesis of Substituted Dihydropyrimidine-2(1H)-ones
Asian Journal of Chemistry,
Vol. 22 No. 1 (2010): Vol 22 Issue 1, 2010
Abstract
Phosphorus pentaoxide catalyzed and microwave enhanced three component Biginelli reaction of aldehyde, 1,3-dicarbonyl compounds and urea or thiourea under reflux microwave conditions to afford dihydropyrimidin-2-(1H)-ones in excellent yield is described. The improved procedure is fairly simple, facile and environment friendly.
Keywords
One pot synthesis
Dihydropyrimidines
Microwave irradiation
P2O5.
NAZERUDDIN*, G., & PANDHARPATTE, M. (2009). Efficient P2O5 Catalyzed Microwave Assisted One Pot Synthesis of Substituted Dihydropyrimidine-2(1H)-ones. Asian Journal of Chemistry, 22(1), 283–287. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/16645
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