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Vol. 30 No. 4 (2018): Vol 30 Issue 4

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Synthesis, Characterization, Antimicrobial and Cytoxic Activities of Copper(II) Isocynate Complex of Schiff Base

https://doi.org/10.14233/ajchem.2018.21020
M.S.N.A. Prasad
Department of Engineering Chemistry, A.U. College of Engineering (A), Andhra University, Visakhapatnam-530 003, India
S. Hari Prasad
Department of Engineering Chemistry, A.U. College of Engineering (A), Andhra University, Visakhapatnam-530 003, India
G. Ravi Kumar
Department of Engineering Chemistry, A.U. College of Engineering (A), Andhra University, Visakhapatnam-530 003, India
G. Neeraja
Department of Engineering Chemistry, A.U. College of Engineering (A), Andhra University, Visakhapatnam-530 003, India
B. Kishore Babu
Department of Engineering Chemistry, A.U. College of Engineering (A), Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : M.S.N.A. Prasad

prasad.mukkantis@gmail.com

Asian Journal of Chemistry, Vol. 30 No. 4 (2018): Vol 30 Issue 4

Abstract

In this paper, Schiff base ligand using acetyl acetone, o-phenylenediamine and salicylaldehyde and its copper complex have been synthesized using self-assembly method. The ligand and its copper(II) complex were characterized by spectroscopic techniques. The antimicrobial studies are carried out for ligand and its copper complex, which confirmed that copper complex does not show any activity against bacteria as well as fungal organisms. However, the cytotoxic studies showed that copper complex has good anticancer activity against MCF-7 (breast cancer) cell line.

Keywords

Copper complex Acetyl acetone o-Phenylenediamine Salicylaldehyde Antimicrobial activity Cytotoxic activity
Prasad, M., Prasad, S. H., Kumar, G. R., Neeraja, G., & Babu, B. K. (2018). Synthesis, Characterization, Antimicrobial and Cytoxic Activities of Copper(II) Isocynate Complex of Schiff Base. Asian Journal of Chemistry, 30(4), 811–813. https://doi.org/10.14233/ajchem.2018.21020
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