Syntheses of Some Thiazolidin-4-ones as Potential Antimicrobial Agents
Corresponding Author(s) : Freddy H. Havaldar
drfreddy_11@yahoo.co.in
Asian Journal of Chemistry,
Vol. 23 No. 3 (2011): Vol 23 Issue 3
Abstract
4-Acetamido-2-methoxybenzoyl hydrazine (1) on condensation with different aromatic aldehydes yielded the substituted benzal-(4'-acetamido-2'-methoxybenzoyl)hydrazines (2a-f) which on cyclization with thioglycolic acid in presence of anhydrous aluminium chloride as catalyst afforded 2-(substituted phenyl)-3-(4'-acetamido-2'-methoxy benzamido)-5-H-thiazolidin-4-ones (3a-f). The structures of the newly synthesized compounds have been established by analytical and spectral methods. These compounds have also been screened for their biological activity.
Keywords
Synthesis
Thiazolidin-4-ones
Antibacterial and antifungal activity
H. Havaldar, F., & Kumar S. Sharma, A. (2010). Syntheses of Some Thiazolidin-4-ones as Potential Antimicrobial Agents. Asian Journal of Chemistry, 23(3), 1314–1316. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/16086
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