Ionic Liquid, [bmim]Br, as An Efficient Promoting Medium for Synthesis of 2-Amino-3,5-dicarbonitrile-6-thiopyridines
Corresponding Author(s) : P. Attar
attar_paria@yahoo.com
Asian Journal of Chemistry,
Vol. 23 No. 3 (2011): Vol 23 Issue 3
Abstract
A simple, efficient and rapid method for the synthesis of 2-amino-3,5-dicarbonitrile-6- thiopyridines through one-pot multi-component reaction of a variety of aryl aldehydes with malononitrile and thiophenol in the presence of ionic liquid 1-butyl-3-methylimidazolium bromide, [bmim]Br, as an efficient promoting medium without the use of any catalyst has been developed. This method has the advantages of good yields, milder reaction conditions, no catalyst and environmentally benign procedure.
Keywords
[Bmim]Br
Ionic liquids
Multi-component reactions
2-Amino-3,5-dicarbonitrile- 6-thiopyridines
Davoodnia, A., Attar, P., Eshghi, H., Morsali, A., Tavakoli-Hoseini, N., & Tavakoli-Nishaburi, A. (2010). Ionic Liquid, [bmim]Br, as An Efficient Promoting Medium for Synthesis of 2-Amino-3,5-dicarbonitrile-6-thiopyridines. Asian Journal of Chemistry, 23(3), 1273–1275. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/16080
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