Microwave-Assisted Synthesis of 2,4,5-Triphenyl-1H-imidazole Containing Schiff Base Derivatives with Potential Antioxidant and Anticancer Activities
Corresponding Author(s) : A. Sivakumar
profaskumar09@gmail.com
Asian Journal of Chemistry,
Vol. 23 No. 3 (2011): Vol 23 Issue 3
Abstract
2-(2,4,5-Triphenyl-1H-imidazol-1-yl)acetohydrazide (3) was utilized as key intermediate for the synthesis of some new Schiff bases 4a-k and 5 under reflux temperature as well as microwave irradiation. All the synthesized compounds were characterized by IR, 1H NMR, 13C NMR and HRMS spectral studies. The antioxidant and anticancer activities of these newly synthesized Schiff base derivatives containing 2,4,5-triphenyl-1H-imidazole moiety have been evaluated.
Keywords
Schiff base
Microwave irradiation
Antioxidant activity
2,4,5-Triphenyl-1H-imidazole
Anticancer activity
Satyanarayana1, V., Rakshit, M., & Sivakumar, A. (2010). Microwave-Assisted Synthesis of 2,4,5-Triphenyl-1H-imidazole Containing Schiff Base Derivatives with Potential Antioxidant and Anticancer Activities. Asian Journal of Chemistry, 23(3), 1212–1218. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/16044
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