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Vol. 23 No. 2 (2011): Vol 23 Issue 2

Lignans from the Stem of Styrax japonica

Na Wu
School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China
Lan Wang
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China
Yong-Kuang Chzn
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China
Zhen Liao
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China
Guang-Yu Yang
School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China
Qiu-Fen Hu
School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming 650031, P.R. China ; Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming 650106, P.R. China

Corresponding Author(s) : Guang-Yu Yang

Asian Journal of Chemistry, Vol. 23 No. 2 (2011): Vol 23 Issue 2

Abstract

A new lignan (Styrlignan A), together with four known lignans, were isolated from the steam of Styrax japonica (Styracaceae). Their structures were determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. The anti HIV-1 activity of Styrlignan A was also evaluated and it shows an anti HIV-1 activity with a TI (therapeutic index) above 38.5.

Keywords

Lignans Styrax japonica Anti HIV-1 activity
(1)
Wu, N.; Wang, L.; Chzn, Y.-K.; Liao, Z.; Yang, G.-Y.; Hu, Q.-F. Lignans from the Stem of Styrax Japonica. ajc 2010, 23, 931-932.
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