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Vol. 32 No. 11 (2020): Vol 32 Issue 11

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Chemometric Profile of Calotropis gigantea and its Antioxidant Activity through Bioactive Compounds from Latex, Leaves and Flower Extracts

https://doi.org/10.14233/ajchem.2020.22875
V. Prabhu
PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India
V. Manjula
PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India
K. Santhiya
PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India
G.P. Tamileela Kanali
PG Department of Chemistry, Nallamuthu Gounder Mahalingam College, Pollachi-642001, India
P. Saravanakumar
Department of Chemistry, Sri Shakthi Institute of Engineering and Technology, Coimbatore-641062, India
G. Sibi
Department of Biotechnology, Indian Academy Degree College (Autonomous), Bengaluru-560043, India

Corresponding Author(s) : G. Sibi

gsibii@gmail.com

Asian Journal of Chemistry, Vol. 32 No. 11 (2020): Vol 32 Issue 11

Abstract

In present study, antioxidant effect was compared among latex, leaf and flower extract of Calotropis gigantea and is first report on comparing the chemometric profiling of various parts of C. gigantea. Ethanol and chloroform extracts of C. gigantea revealed the presence of 28 different chemotypes in latex, 27 in leaves and 32 in flowers. Major phtyochemicals present were of which fatty acid ethyl esters, fatty alcohols, terpenes, coumarins and carbocycles. C. gigantea leaf extract recorded 78% of 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and IC50 values of 14.44, 6.74 and 21.35 μg/mL were observed for latex, leaves and flower extracts respectively. For 2,2′-azinobis-(3-ethylbenzthiazolin-6-sulfonic acid) [ABTS+] assay, IC50 values ranged between 6.74 and 21.25 μg/mL by various components of C. gigantea. The results represent free radical-scavenging activities of extracts of several parts of C. gigantea. The findings will definitely use in new directions in pharmacological and therapeutic investigations on C. gigantea latex, leaves and flowers.

Keywords

Calotropis gigantea Antioxidant activity Latex Fatty acid esters
Prabhu, V., Manjula, V., Santhiya, K., Tamileela Kanali, G., Saravanakumar, P., & Sibi, G. (2020). Chemometric Profile of Calotropis gigantea and its Antioxidant Activity through Bioactive Compounds from Latex, Leaves and Flower Extracts. Asian Journal of Chemistry, 32(11), 2865–2872. https://doi.org/10.14233/ajchem.2020.22875
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