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Vol. 32 No. 9 (2020): Vol 32 Issue 9, 2020

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Antioxidant Activity of Piperazine Compounds: A Brief Review

https://doi.org/10.14233/ajchem.2020.22832
Shaheen Begum
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India
M.S. Rashida Anjum
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India
G. Poojitha Harisree
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India
N. Sivalakshmi
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India
P. Priyanka
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India
K. Bharathi
Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, India

Corresponding Author(s) : Shaheen Begum

shaheen.pharmchem@gmail.com

Asian Journal of Chemistry, Vol. 32 No. 9 (2020): Vol 32 Issue 9, 2020

Abstract

Piperazine ring is found in several potent antioxidant molecules. Literature survey revealed that the piperazine ring has been coupled to different heterocyclic rings such as quinoline, pyridine, pyrazine, azole, 1,3,4-oxadiazole, 1,4-benzodioxane, pyrrolidinone, benzimidazole, pyrazine benzimidazole to obtain compounds with good antioxidant activity. It is found that the natural compounds like α-lipoic acid, methylxanthine, berberine, sarsasapogenin, chrysin, chromen-4-one, co-enzyme Q when attached to piperazine ring, antioxidant activity was improved. In the present article, piperazine containing antioxidant molecules were reviewed.

Keywords

Piperazine Piperazine Free radical scavenging Free radical scavenging Antioxidant Antioxidant
Begum, S., Rashida Anjum, M., Poojitha Harisree, G., Sivalakshmi, N., Priyanka, P., & Bharathi, K. (2020). Antioxidant Activity of Piperazine Compounds: A Brief Review. Asian Journal of Chemistry, 32(9), 2105–2118. https://doi.org/10.14233/ajchem.2020.22832
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