Comparative Study of UV Spectrophotometric Methods for the Determination of Ethamsylate in Bulk and Pharmaceutical Formulations
Corresponding Author(s) : R. Nageshwara Rao
Asian Journal of Chemistry,
Vol. 16 No. 3 (2004): Vol 16 Issue 3
Abstract
Two simple, sensitive and reproducible UV spectrophotometric methods (A and B) for the determination of ethamsylate (EMS) in bulk samples and pharmaceutical formulations are described. EMS was taken in methanol for method A and in 0.1 N HCl for method B. The maximum absorbance was observed at 302 nm for method A and 302 nm for method B. Regression analysis of Beer’s law plots showed good concentration ranges 2–10 μg/mL for method A and 5–15 μg/mL for method B respectively. There is no interference from any common pharmaceutical excipients.
Keywords
UV spectrophotometric methods
Ethamsylate
Nageshwara Rao, R., Nagaraju, P., Srinivasulu, C., Jitendra Kumar, P., Suresh, V., & Sireesha, D. (2016). Comparative Study of UV Spectrophotometric Methods for the Determination of Ethamsylate in Bulk and Pharmaceutical Formulations. Asian Journal of Chemistry, 16(3), 1956–1958. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/14449
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