UV Spectrophotometric Methods for the Determination of Lercanidipine and Isradipine in Bulk and Pharmaceutical Formulations

R. Nageswara Rao; P. Nagaraju; C. Srinivasulu; P. Radhakrishnamurthy; D. Sireesha; S. Uday Bhaskar

Issue

Vol. 16 No. 3 (2004): Vol 16 Issue 3

Issue Published : June 1, 2004

UV Spectrophotometric Methods for the Determination of Lercanidipine and Isradipine in Bulk and Pharmaceutical Formulations

R. Nageswara Rao

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

P. Nagaraju

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

C. Srinivasulu

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

P. Radhakrishnamurthy

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

D. Sireesha

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

S. Uday Bhaskar

Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences, Berhampur, At/PO Mohuda, Dist. Ganjam-760 002, India

Corresponding Author(s) : R. Nageswara Rao

Asian Journal of Chemistry, Vol. 16 No. 3 (2004): Vol 16 Issue 3
Article Published : June 11, 2016

Abstract

Simple and sensitive UV spectrophotometric methods have been developed for the determination of two anti-hypertensive drugs, namely, lercanidipine and isradipine in bulk and their formulations. Both the drugs were taken in methanol solution and maximum absorbance was observed at 236 nm and 327 nm respectively. Beer’s law was obeyed in the concentration of 2–10 μg/mL for lercanidipine and 2–10 μg/mL for isradipine. There is no interference from any common pharmaceutical additives and diluents.

Keywords

UV spectrophotometric methods Lercanidipine Isradipine

Nageswara Rao, R., Nagaraju, P., Srinivasulu, C., Radhakrishnamurthy, P., Sireesha, D., & Uday Bhaskar, S. (2016). UV Spectrophotometric Methods for the Determination of Lercanidipine and Isradipine in Bulk and Pharmaceutical Formulations. Asian Journal of Chemistry, 16(3), 1950–1952. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/14447

Issue

Vol. 16 No. 3 (2004): Vol 16 Issue 3

UV Spectrophotometric Methods for the Determination of Lercanidipine and Isradipine in Bulk and Pharmaceutical Formulations

Corresponding Author(s) : R. Nageswara Rao

Abstract

Keywords

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