Hypoglycemic Activity and Brine Shrimp Lethality of (7E,11E,1R,2S,3R,4R,14S)-14-Acetoxy-3,4-epoxycembra-7,11,15-triene-17,2-Olide: A Metabolite of Lobophytum crassum†
Corresponding Author(s) : Gottumukkala V. Subbaraju
subbaraju@nettlinx.com
Asian Journal of Chemistry,
Vol. 16 No. 3 (2004): Vol 16 Issue 3
Abstract
Hypoglycemic activity and brine shrimp lethality of ethyl acetate soluble fraction of Lobophytum crassum and its active constituent (7E,11E,1R,2S,3R,4R,14S)-14-acetoxy-3,4-epoxycembra-7,11,15-triene-17,2-olide were tested. Both ethyl acetate fraction and cembranoid diterpene exhibited moderate hypoglycemic activity whereas cembranoid diterpene exhibited potent activity in brine shrimp lethality assay.
Keywords
Lobophytum crassum
Artemia salina
Indian Ocean
Hypoglycemic activity
Sucrose tolerance test
V. Krishnaraju, A., V.N. Rao, T., Vanisree, M., & V. Subbaraju, G. (2016). Hypoglycemic Activity and Brine Shrimp Lethality of (7E,11E,1R,2S,3R,4R,14S)-14-Acetoxy-3,4-epoxycembra-7,11,15-triene-17,2-Olide: A Metabolite of Lobophytum crassum†. Asian Journal of Chemistry, 16(3), 1311–1314. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/14372
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