Spectrophotometric Estimation of Sisomicin and Olanzapine

D. Gowri Sankar; J.M. Rajendra Kumar; P.V.M. Latha

Issue

Vol. 17 No. 2 (2005): Vol 17 Issue 2

Issue Published : December 30, 2004

Spectrophotometric Estimation of Sisomicin and Olanzapine

D. Gowri Sankar

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

J.M. Rajendra Kumar

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

P.V.M. Latha

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : D. Gowri Sankar

Asian Journal of Chemistry, Vol. 17 No. 2 (2005): Vol 17 Issue 2
Article Published : January 31, 2016

Abstract

A simple and sensitive spectrophotometric method has been developed for the estimation of sisomicin and olanzapine in pure and pharmaceutical formulations. This method is based on the formation of blue coloured species with Folin-Ciocalteu reagent under alkaline conditions exhibiting maximum absorbance at 725 nm and 655 nm. Beer’s law is obeyed at the concentration range of 10–50 μg/mL for sisomicin and 1.5–7.5 μg/mL for olanzapine. The method has been statistically evaluated and is found to be precise and accurate.

Keywords

Spectrophotometric estimation Sisomicin Olanzapine

Gowri Sankar, D., Rajendra Kumar, J., & Latha, P. (2016). Spectrophotometric Estimation of Sisomicin and Olanzapine. Asian Journal of Chemistry, 17(2), 1331–1333. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/14355

Issue

Vol. 17 No. 2 (2005): Vol 17 Issue 2

Spectrophotometric Estimation of Sisomicin and Olanzapine

Corresponding Author(s) : D. Gowri Sankar

Abstract

Keywords

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