A Facile and Fast One Flask Synthesis of Unsaturated Azlactones by Microwave Activation
Corresponding Author(s) : Pradeep K. Tripathy
pkt@nerist.ernet.in
Asian Journal of Chemistry,
Vol. 17 No. 3 (2005): Vol 17 Issue 3
Abstract
2-Substituted-2-oxazolin-5-ones (2), generated by cyclizing a-N-acylaminoacids (1) with ethylchloroformate in the presence of triethylamine in benzene, affords 2-substituted-4-arylmethylene-2-oxazolin-5-ones (3), on reaction with aromatic aldehydes by microwave irradiation. All the steps are carried out in one flask.
Keywords
a-N-acrylaminoacids
Azlactone
Oxazolones
2-Substituted 4-arylmethylene-2-oxazolin-5-ones
Microwave activation
(1)
K. Tripathy, P. A Facile and Fast One Flask Synthesis of Unsaturated Azlactones by Microwave Activation. ajc 2016, 17, 2037-2039.
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