Synthesis, Characterization and Antibacterial Studies of Transition Metal Complexes of Mannich Base

Abstract

A new series of complexes of Fe(III), Co(II), Ni(II), Cu(I), Zn(II), Hg(II), Pb(II) and Ag(I) with 3-morpholinomethyl-5-(b-naphthoxy)methyl-1,3,4-oxadia-2-thione have been synthesized. Characterization of these complexes was carried out by elemental analyses, magnetic susceptibility measurements, thermogravimetric, UV-Vis, IR and ¹H NMR spectral studies. Though the ligand is potentially polydentate, in the complexes studied, it behaves as a monodentate ligand––bonding either through N(4) of the oxadiazole moitey or through S of the thione group––or as a bidentate bridging ligand. Tetrahedral structures for Fe(III), Co(II), Ni(II), Cu(I), Zn(II), Hg(II) and Pb(II) complexes, tetrahedral polymeric structure for Cd(II) and linear structure for Ag(I) complex have been proposed. Antibacterial studies of the ligand and Fe(III), Co(II), Cu(I) and Zn(II) complexes were also carried out.