Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Y. Prasanna Raju; G. Asuntha; B. Sreenivasa Rao; K.V. Ramana Murthy

Issue

Vol. 17 No. 3 (2005): Vol 17 Issue 3

Issue Published : March 19, 2005

Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Y. Prasanna Raju

Department of Pharmaceutical Chemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, (Via) Tirupati-517 102, India

G. Asuntha

S.W.P. Polytechnic, Tirupati-517 502, India

B. Sreenivasa Rao

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

K.V. Ramana Murthy

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : Y. Prasanna Raju

kanishka9002@yahoo.com

Asian Journal of Chemistry, Vol. 17 No. 3 (2005): Vol 17 Issue 3
Article Published : May 13, 2016

Abstract

Rofecoxib is a non-steroidal antiinflammatory drug and selective cox-2 inhibitor, used in the treatment of rheumatoid arthritis especially in gastritis and ulcerative conditions. It is chemically designated as 4-[4-(methylsulfonyl) phenyl]-3-phenyl-2-(5H)-furanone. In this present study, dissolution of rofecoxib from two commercial formulations was studied in two different media to evaluate their discriminating power.

Keywords

Rofecoxib Dissolution Formulation medium

Prasanna Raju, Y., Asuntha, G., Sreenivasa Rao, B., & Ramana Murthy, K. (2016). Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations. Asian Journal of Chemistry, 17(3), 1785–1788. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/14044

Issue

Vol. 17 No. 3 (2005): Vol 17 Issue 3

Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Corresponding Author(s) : Y. Prasanna Raju

Abstract

Keywords

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