Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Y. Prasanna Raju; G. Asuntha; B. Sreenivasa Rao; K.V. Ramana Murthy

Issue

Vol. 17 No. 3 (2005): Vol 17 Issue 3

Issue Published : 19 March 2005

Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Y. Prasanna Raju

Department of Pharmaceutical Chemistry, Sree Vidyanikethan College of Pharmacy, A. Rangampet, (Via) Tirupati-517 102, India

G. Asuntha

S.W.P. Polytechnic, Tirupati-517 502, India

B. Sreenivasa Rao

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

K.V. Ramana Murthy

Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, India

Corresponding Author(s) : Y. Prasanna Raju

kanishka9002@yahoo.com

Asian Journal of Chemistry, Vol. 17 No. 3 (2005): Vol 17 Issue 3
Article Published : 13 May 2016

Abstract

Rofecoxib is a non-steroidal antiinflammatory drug and selective cox-2 inhibitor, used in the treatment of rheumatoid arthritis especially in gastritis and ulcerative conditions. It is chemically designated as 4-[4-(methylsulfonyl) phenyl]-3-phenyl-2-(5H)-furanone. In this present study, dissolution of rofecoxib from two commercial formulations was studied in two different media to evaluate their discriminating power.

Keywords

Rofecoxib Dissolution Formulation medium

(1)

Prasanna Raju, Y.; Asuntha, G.; Sreenivasa Rao, B.; Ramana Murthy, K. Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations. ajc 2016, 17, 1785-1788.

Issue

Vol. 17 No. 3 (2005): Vol 17 Issue 3

Development of Dissolution Medium for Rofecoxib in Pharmaceutical Formulations

Corresponding Author(s) : Y. Prasanna Raju

Abstract

Keywords

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