UV-Spectrophotometric Determination of Esomeprazole in Tablet Dosage Forms
Corresponding Author(s) : P. MOHAN RAJ
veeru6in@rediffmail.com
Asian Journal of Chemistry,
Vol. 19 No. 4 (2007): Vol 19 Issue 4
Abstract
A new, simple ,sensitive UV-spectrophotometric method has been developed for the determination of esomeprazole in bulk and in its dosage form. Esomeprazole shows maximum absorbance at 275 nm in dimethyl formamide solvent for stock solution and further dilution with 50:50 (v/v) of DMF: distilled water. Beer’s law obeyed in the concentration range of 10-50 mcg/mL. Results of analysis were validated statistically and by recovery studies.
Keywords
Esomerozole
Spectrophotometric determination
MOHAN RAJ, P., VEERESWARA RAO, R., MUKHERJEE, P., SARVANAN, V., GOPAL, N., M. KALYANKAR, T., & SHIVAKUMAR, T. (2010). UV-Spectrophotometric Determination of Esomeprazole in Tablet Dosage Forms. Asian Journal of Chemistry, 19(4), 3250–3252. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/13492
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