Variations in the Physico-chemical Parameters of Some 5a and 5b Substituted Barbiturate Derivatives

RAKESH RAY; S. HARI KRISHNA; J.D. SHARMA; S.N. LIMAYE

Issue

Vol. 19 No. 4 (2007): Vol 19 Issue 4

Issue Published : February 3, 2007

Variations in the Physico-chemical Parameters of Some 5a and 5b Substituted Barbiturate Derivatives

RAKESH RAY

Forensic Science and Chemistry, Dr. H.S. Gour University, Sagar-470 003, India

S. HARI KRISHNA

Forensic Science and Chemistry, Dr. H.S. Gour University, Sagar-470 003, India

J.D. SHARMA

Forensic Science and Chemistry, Dr. H.S. Gour University, Sagar-470 003, India

S.N. LIMAYE

Forensic Science and Chemistry, Dr. H.S. Gour University, Sagar-470 003, India

Corresponding Author(s) : S.N. LIMAYE

snl222@yahoo.co.in

Asian Journal of Chemistry, Vol. 19 No. 4 (2007): Vol 19 Issue 4
Article Published : March 30, 2010

Abstract

The barbiturates are therapeutically used as sedative, hyponotic, anaesthetic and anticonvulsant agents. The trienolmoiety and 5-substituents regulate the biological activity regarding the lypophilicity/hydrophobicity values of barbiturates against their physico-chemical properties.

Keywords

Modelling Hydrophobicity Therapeutic Barbiturates

RAY, R., HARI KRISHNA, S., SHARMA, J., & LIMAYE, S. (2010). Variations in the Physico-chemical Parameters of Some 5a and 5b Substituted Barbiturate Derivatives. Asian Journal of Chemistry, 19(4), 2497–2501. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/13334

Issue

Vol. 19 No. 4 (2007): Vol 19 Issue 4

Variations in the Physico-chemical Parameters of Some 5a and 5b Substituted Barbiturate Derivatives

Corresponding Author(s) : S.N. LIMAYE

Abstract

Keywords

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