Issue

Vol. 29 No. 12 (2017): Vol 29 Issue 12

Copyright (c) 2017 AJC

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Antioxidant Properties of Indole-3-Acetic Acid based Biopolymeric Hydrogels

https://doi.org/10.14233/ajchem.2017.20751
G. Chitra
Department of Chemistry, Bangalore College of Engineering and Technology, Chandapura, Bangalore-560 081, India
D.S. Franklin
Department of Chemistry, C. Abdul Hakeem College of Engineering and Technology, Melvisharam-632 509, India
S. Sudarsan
Department of Chemistry, C. Abdul Hakeem College of Engineering and Technology, Melvisharam-632 509, India
M. Sakthivel
Research and Development Centre, Bharathiar University, Coimbatore-641 046, India
S. Guhanathan
PG & Research Department of Chemistry, Muthurangam Government Arts College, Vellore-632 002, India

Corresponding Author(s) : S. Guhanathan

sai_gugan@yahoo.com

Asian Journal of Chemistry, Vol. 29 No. 12 (2017): Vol 29 Issue 12

Abstract

A series of novel indole-3-acetic acid based hydrogel was synthesized by condensation polymerization without cross-linker. The polymeric hydrogel was prepared using citric acid, indole-3-acetic acid and triethylene glycol with equimolar composition. The hydrogel revealed a pH-sensitive swelling behaviour, with increased swelling in acidic media and then decreased swelling in basic media. The biopolymeric hydrogels were characterized by Fourier transform infrared (FT-IR) spectroscopy, 1H NMR, 13C NMR and TGA-DTA. The antioxidant activity has evaluated by DPPH and NO radical assay at different concentration compared with ascorbic acid, which has shown excellent antioxidant property.

Keywords

Hydrogel Indole-3-acetic acid Swelling equilibrium Antioxidant activity
Chitra, G., Franklin, D., Sudarsan, S., Sakthivel, M., & Guhanathan, S. (2017). Antioxidant Properties of Indole-3-Acetic Acid based Biopolymeric Hydrogels. Asian Journal of Chemistry, 29(12), 2647–2650. https://doi.org/10.14233/ajchem.2017.20751
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX
References
  1. O. Wichterle and D. Lim, Nature, 185, 117 (1960); https://doi.org/10.1038/185117a0.
  2. T. Inoue, G. Chen, K. Nakamae and A. Hoffman, J. Control. Rel., 49, 167 (1997); https://doi.org/10.1016/S0168-3659(97)00072-2.
  3. J. Wang and W. Wu, Eur. Polym. J., 41, 1143 (2005); https://doi.org/10.1016/j.eurpolymj.2004.11.034.
  4. S. Simon and J. Petrasek, Plant Sci., 180, 454 (2011); https://doi.org/10.1016/j.plantsci.2010.12.007.
  5. J.S. Sidhu, R. Singla, Mayank and V. Jaitak, Anticancer. Agents Med. Chem., 16, 160 (2015); https://doi.org/10.2174/1871520615666150520144217.
  6. I. Chen, S. Safe and L. Bjeldanes, Biochem. Pharmacol., 51, 1069 (1996); https://doi.org/10.1016/0006-2952(96)00060-3.
  7. M.S. Estevão, L.C. Carvalho, D. Ribeiro, D. Couto, M. Freitas,A. Gomes, L.M. Ferreira, E. Fernandes and M.M. Marques, Eur. J. Med. Chem., 45, 4869 (2010); https://doi.org/10.1016/j.ejmech.2010.07.059.
  8. G. Giagoudakis and S.L. Markantonis, Pharmacotherapy, 25, 18 (2005); https://doi.org/10.1592/phco.25.1.18.55618.
  9. E. Buyukbingol, S. Suzen and G. Klopman, IL Farmaco, 49, 443 (1994).
  10. G. Chitra, D.S. Franklin, S. Sudarsan, M. Sakthivel and S. Guhanathan, Int. J. Biol. Macromol., 95, 363 (2017); https://doi.org/10.1016/j.ijbiomac.2016.11.068.
  11. G. Chitra, D.S. Franklin and S. Guhanathan, J. Macromol. Sci. Part A Pure Appl. Chem., 54, 151 (2017); https://doi.org/10.1080/10601325.2017.1265401.
  12. S. Olgen, Z. Kilic, A.O. Ada and T. Coban, Arch. Pharm. Chem. Life Sci., 340, 140 (2007); https://doi.org/10.1002/ardp.200600176.
  13. M.A. Babizhayev, A.I. Deyev, V.N. Yermakova, I.V. Brikman and J. Bours, Drugs, 5, 125 (2004).
  14. I. Liu and M. Meydani, Nutr. Rev., 60, 368 (2002); https://doi.org/10.1301/00296640260385810.
  15. B. Halliwell and J.M.C. Gutteridge, Arch. Biochem. Biophys., 280, 1 (1990); https://doi.org/10.1016/0003-9861(90)90510-6.
  16. A.A. El-Kheshen and S.F.G. El-Rab, Der. Pharma Chem., 4, 53 (2012).
  17. M.S. Blois, Nature, 181, 1199 (1958); https://doi.org/10.1038/1811199a0.
  18. S.K. Bajpai and S. Singh, React. Funct. Polym., 66, 431 (2006); https://doi.org/10.1016/j.reactfunctpolym.2005.09.003.
  19. S. Ekici, Polym. Int., 61, 1758 (2012); https://doi.org/10.1002/pi.4267.
  20. M. Sadeghi, N. Ghasemi, M. Kazemi and F. Soleimani, Middle East J. Sci. Res., 11, 311 (2012).
  21. J. Yang, A.R. Webb and G.A. Ameer, Adv. Mater., 16, 511 (2004); https://doi.org/10.1002/adma.200306264.
  22. W. Wang and A. Wang, Carbohydr. Polym., 80, 1028 (2010); https://doi.org/10.1016/j.carbpol.2010.01.020.
  23. D.S. Franklin and S. Guhanathan, Iran. Polym. J., 23, 809 (2014); https://doi.org/10.1007/s13726-014-0278-z.
  24. R.J. Abraham, J.J. Byrne, L. Griffiths and R. Koniotou, Magn. Reson. Chem., 43, 611 (2005); https://doi.org/10.1002/mrc.1611.
  25. R. Indira, T. Tamizharuvi, T.V. Rajendran and V. Jaisankar, Indian J. Adv. Chem. Sci., 1, 250 (2013).
  26. M. Kelen and N. Sanli, J. Braz. Chem. Soc., 20, 133 (2009); https://doi.org/10.1590/S0103-50532009000100021.
  27. J. Yang, D. Motlagh, J.B. Allen, A.R. Webb, M.R. Kibbe, O. Aalami, M. Kapadia, T.J. Carroll and G.A. Ameer, Adv. Mater., 18, 1493 (2006); https://doi.org/10.1002/adma.200600230.
  28. S. Nesrinne and A. Djamel, Arab. J. Chem., 10, 539 (2013); https://doi.org/10.1016/j.arabjc.2013.11.027.
  29. H.K. Ju, S.Y. Kim and Y.M. Lee, Polymer, 42, 6851 (2001); https://doi.org/10.1016/S0032-3861(01)00143-4.
  30. D.S. Franklin and S. Guhanathan, J. Appl. Polym. Sci., 132, 41921 (2015); https://doi.org/10.1002/app.41921.
  31. S.H. Hosseini and M. Ashjari, Int. J. Phys. Sci., 8, 1611 (2013).
  32. A. Pourjavadi and G.R. Mahdavinia, Turk. J. Chem., 30, 595 (2006).
  33. J.H. Sung, M.R. Hwang, J.O. Kim, J.H. Lee, Y.I. Kim, J.H. Kim, J.W. Chang, S.G. Jin, J.A. Kim, W.S. Lyoo, S.S. Han, S.K. Ku and S. Yong, Int. J. Pharm., 392, 232 (2010); https://doi.org/10.1016/j.ijpharm.2010.03.024.
  34. R.M. Patel and N.J. Patel, J. Adv. Pharm. Educ. Res., 1, 52 (2011).
  35. M.B. Arnao, Trends Food Sci. Technol., 11, 419 (2000); https://doi.org/10.1016/S0924-2244(01)00027-9.
Read More
Author biographies is not available.
Download
PDF
Statistic
Read Counter : 0 Download : 0