Synthesis and Characterization of Cu(II), Ni(II), Co(II), Mn(II), Zn(II), Cd(II) Complexes of Isonicotinoylhydrazone-1-methyl-2-aldehydepyrrole

Abstract

A series of complexes of Cu(II), Ni(II), Co(II), Mn(II), Zn(II), Cd(II) with Isonicotinoylhydrazone-1-methyl-2-aldehydepyrrole (INHMAP) formed by condensation of isonicotinoylhydrazine with 1-methyl-2-aldehydepyrrole has been reported. All the complexes have been characterized by analytical data, IR, UV-VIS, NMR, magnetic susceptibility, thermal analysis and for Cu(II) complex by the ESR spectrum. For all complexes the antimicrobial activity have been tested as for the bacterias Staphylococcus aureus, Escherichia coli and Proteus vulgaris. Experimental data suggest the stoichiometry of 1:2 (metal:ligand) for the complexes of Cu(II), Co(II) and of 1:1 for the complexes of Ni(II), Mn(II), Zn(II), Cd(II). Electronic spectra and magnetic moments suggest octahedral stereochemistry for Cu(II), Co(II), tetrahedral configuration for the complexes of Mn(II), Zn(II), Cd(II) and square-planar geometry to the Ni(II) complex. From IR spectra results, it is concluded that the INHMAP ligand is coordinated at the metalic ions by oxygen amide (C=O) and the azomethine nitrogen.