Synthesis, Characterization and Biological Studies of New Schiff Bases and Azetidinones Derived from Propionic Acid Derivatives
Corresponding Author(s) : Neeraj Kumar Fuloria
nfuloria@rediffmail.com; nfuloria@yahoo.com
Asian Journal of Chemistry,
Vol. 20 No. 8 (2008): Vol 20 Issue 8
Abstract
Phenyl propionohydrazide (2), a hydrazinated derivative of methyl phenyl propanoate (1), when refluxed with aromatic aldehydes yielded Schiff bases 3A-E, which on subsequent cyclization with triethylamine and chloroacetylchloride yielded azetidinones 4A-E. The novel series of compounds were elucidated on the basis of spectral studies and screened for antibacterial and antifungal studies.
Keywords
Phenyl propionohydrazide
Methyl phenyl propanoate
Schiff base
Azetidinones
Antibacterial and Antifungal activity
Kumar Fuloria, N., Singh, V., Shaharyar, M., & Ali, M. (2010). Synthesis, Characterization and Biological Studies of New Schiff Bases and Azetidinones Derived from Propionic Acid Derivatives. Asian Journal of Chemistry, 20(8), 6457–6462. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12996
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