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Synthesis, Characterization and Antimicrobial Studies of Mannich Base Derived from 2-Methyl Benzimidazole and its Metal Complexes
Corresponding Author(s) : S.J. Askar Ali
Asian Journal of Chemistry,
Vol. 29 No. 11 (2017): Vol 29 Issue 11
Abstract
A ligand derived from 2-methyl benzimidazole, nicotinic acid hydrazide and benzaldehyde and its metal complexes with Cu(II), Co(II), Ni(II), Zn(II) and Fe(III) have been synthesized and characterized by IR, UV-visible, 1H NMR, 13C NMR. The antimicrobial activitives of the ligand and its metal complexes were determined against the bacteria Escherichia coli, Salmonella paratyphi A and Staphylococcus aureus.
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- A.M.A. Khadar, J. Gowda, K. Balakrishna and S.N. Kumar, Indian J. Chem., 49A, 1130 (2010).
- S.A. Khan and A. Nandan, Indian J. Heterocycl. Chem., 7, 55 (1997).
- V. Gunasekaran, J.T. Leonard, O.S. Rajesh and L. Jeyaseel, Asian J. Chem., 19, 116 (2007).
- Y. Murthi, R. Arora and D. Pathak, J. Indian Chem. Soc., 87, 627 (2010).
- V.K. Pandey, V.D. Gupta and D.N. Tiwari, Indian J. Heterocycl. Chem., 14, 217 (2005).
- H. Marijana, P. Gordana, M. Marko, K. Marijeta and G. Karminski-Zamola, ChemInform, 41, 230 (2010); https://doi.org/10.1002/chin.201039155.
- D.J. Abraham, Burger’s Medicinal Chemistry and Drug Discovery, John Wiley, vol. 6, p. 180 (2003).
- P.N. Preston, Chem. Rev., 74, 279 (1974); https://doi.org/10.1021/cr60289a001.
- K.C. Rout, R.R. Mohanty, S. Jena and K.C. Dash, Polyhedron, 15, 1023 (1996); https://doi.org/10.1016/0277-5387(95)00173-2.
- H. Chang, M. Fu, X.J. Zhao and E.C. Yang, J. Coord. Chem., 63, 3551 (2010); https://doi.org/10.1080/00958972.2010.515214.
- F.M. Nie, J. Chen, Z. Li and F. Lu, J. Coord. Chem., 63, 1711 (2010); https://doi.org/10.1080/00958972.2010.488690.
- M.Y. Duan, J. Li, Y. Xi, X.F. Lu, J.Z. Liu, G. Mele and F.X. Zhang, J. Coord. Chem., 63, 90 (2010); https://doi.org/10.1080/00958970903302707.
- M. Akkurt, S. Karaca, H. Kucukbay, E. Orhan, O. Buyukgungor, Acta Cryst., E61, m41 (2005); https://doi.org/10.1107/S1600536804031356.
- M. Arif, M.M.R. Qurashi and M.A. Shad, J. Coord. Chem., 64, 1914 (2011); https://doi.org/10.1080/00958972.2011.582867.
- H. Kucukbay, S. Gunal, E. Orhan and R. Durmaz, Asian J. Chem., 22, 7376 (2010).
References
A.M.A. Khadar, J. Gowda, K. Balakrishna and S.N. Kumar, Indian J. Chem., 49A, 1130 (2010).
S.A. Khan and A. Nandan, Indian J. Heterocycl. Chem., 7, 55 (1997).
V. Gunasekaran, J.T. Leonard, O.S. Rajesh and L. Jeyaseel, Asian J. Chem., 19, 116 (2007).
Y. Murthi, R. Arora and D. Pathak, J. Indian Chem. Soc., 87, 627 (2010).
V.K. Pandey, V.D. Gupta and D.N. Tiwari, Indian J. Heterocycl. Chem., 14, 217 (2005).
H. Marijana, P. Gordana, M. Marko, K. Marijeta and G. Karminski-Zamola, ChemInform, 41, 230 (2010); https://doi.org/10.1002/chin.201039155.
D.J. Abraham, Burger’s Medicinal Chemistry and Drug Discovery, John Wiley, vol. 6, p. 180 (2003).
P.N. Preston, Chem. Rev., 74, 279 (1974); https://doi.org/10.1021/cr60289a001.
K.C. Rout, R.R. Mohanty, S. Jena and K.C. Dash, Polyhedron, 15, 1023 (1996); https://doi.org/10.1016/0277-5387(95)00173-2.
H. Chang, M. Fu, X.J. Zhao and E.C. Yang, J. Coord. Chem., 63, 3551 (2010); https://doi.org/10.1080/00958972.2010.515214.
F.M. Nie, J. Chen, Z. Li and F. Lu, J. Coord. Chem., 63, 1711 (2010); https://doi.org/10.1080/00958972.2010.488690.
M.Y. Duan, J. Li, Y. Xi, X.F. Lu, J.Z. Liu, G. Mele and F.X. Zhang, J. Coord. Chem., 63, 90 (2010); https://doi.org/10.1080/00958970903302707.
M. Akkurt, S. Karaca, H. Kucukbay, E. Orhan, O. Buyukgungor, Acta Cryst., E61, m41 (2005); https://doi.org/10.1107/S1600536804031356.
M. Arif, M.M.R. Qurashi and M.A. Shad, J. Coord. Chem., 64, 1914 (2011); https://doi.org/10.1080/00958972.2011.582867.
H. Kucukbay, S. Gunal, E. Orhan and R. Durmaz, Asian J. Chem., 22, 7376 (2010).