Vibrational Spectra and Qualitative Analysis of Albendazole and Mebendazole

Abstract

In this work, vibrational spectral analysis of two broadspectrum anthelmintic drugs albendazole and mebendazole, that fall under the category of the WHO's model list of essential drugs for the eradication of helminthiasis, has been carried out by employing FTIR, FT-Raman and UV-Visible spectroscopic techniques. The change in the quality of the drugs under various storage conditions has been studied by spectral techniques. The results are indicative of the fact that it is essential to store the drugs under the prescribed ones to maintain their quality and the alteration in quality can be assessed by spectroscopy as a tool.