Antiinflammatory Activity of 5-(2'-Hydroxyphenyl)-3-phenyl Pyrazolinates of Co(II), Ni(II), Cu(II): A Comparative Study
Corresponding Author(s) : K.V. Sharma
sharmak_v@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 8 (2008): Vol 20 Issue 8
Abstract
5-(2'-Hydroxyphenyl)-3-phenylpyrazolinates of Co(II), Ni(II), Cu(II) were synthesized, characterized and evaluated for their antiinflammatory activity by the carrageenan induced rat paw edema test. A comparison of 5-(2'-Hydroxyphenyl)- 3-phenylpyrazolinates of Co(II), Ni(II), Cu(II) with Co(II), Ni(II), Cu(II) complexes of diclofenac and plain diclofenac drug reveled that the 5-(2'-hydroxyphenyl)-3-phenyl pyrazolinates of Cu(II) and Co(II) were more effective than the Co(II), Ni(II), Cu(II) complexes of diclofenac and plain diclofenac drug itself.
Keywords
Pyrazolinates
Antiinflammatory activity
Diclofenac
Sharma, K., & Sharma, V. (2010). Antiinflammatory Activity of 5-(2’-Hydroxyphenyl)-3-phenyl Pyrazolinates of Co(II), Ni(II), Cu(II): A Comparative Study. Asian Journal of Chemistry, 20(8), 6213–6216. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12961
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