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Vol. 29 No. 11 (2017): Vol 29 Issue 11

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Chemical Composition and Mosquitocidal Activity of n-Hexane and Methanolic Extracts from Euphorbia anacampseros var. tmolea: An Endemic Species of Turkey against Aedes aegypti

https://doi.org/10.14233/ajchem.2017.20813
Hatice Demiray
Ege University, Faculty of Science, Department of Biology Section of Botany, 35100 Bornova, Izmir, Turkey
Nurhayat Tabanca
USDA-ARS, Subtropical Horticulture Research Station, Miami, FL 33158, USA
Fatih Goger
Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey
Alden S. Estep
Navy Entomology Center of Excellence, CMAVE Detachment, 1700 SW 23rd Drive, Gainesville, FL 32608, USA, USDA-ARS, Center for Medical, Agricultural and Veterinary Entomology, 1700 SW 23rd Drive, Gainesville, FL 32608, USA
James J. Becnel
USDA-ARS, Center for Medical, Agricultural and Veterinary Entomology, 1700 SW 23rd Drive, Gainesville, FL 32608, USA
Betul demirci
Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Turkey

Corresponding Author(s) : Hatice Demiray

haticedemus@yahoo.com

Asian Journal of Chemistry, Vol. 29 No. 11 (2017): Vol 29 Issue 11

Abstract

Volatile composition of the n-hexane and methanol extracts from E. anacampseros var. tmolea was analyzed by head space-solid phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). Chemical characterization of the methanolic extract was determined by LC-ESI-MS/MS. Both extracts were bioassayed against 1st instar larvae and adult female Ae. aegypti. The main components identified from the E. anacampseros var. tmolea n-hexane fraction were 1,8-cineole (27.5 %), p-cymene (25 %), g-terpinene (12.8 %), limonene (9.9 %). Methyl hexanoate (18.8 %), methyl nonanoate (13.3 %), dimethyl succinate (6.5 %), methyl octanoate (6 %) and methyl phenylacetate (5.3 %) were identified from the methanolic fraction. The n-hexane extract showed 100 % mortality at 0.1 μg/μL against 1st instar larvae of Ae. aegypti and the methanolic extract exhibited 83.3 % mortality at 5 μg/mosquito against adult female Ae. aegypti. The bioassay-guided study demonstrates that n-hexane and methanol extracts of E. anacampseros var. tmolea contain compounds with natural mosquito larvicidal and adulticidal activity.

Keywords

Euphorbiaceae Mosquito control Biopesticide Monoterpenes Aliphatic esters
Demiray, H., Tabanca, N., Goger, F., Estep, A. S., Becnel, J. J., & demirci, B. (2017). Chemical Composition and Mosquitocidal Activity of n-Hexane and Methanolic Extracts from Euphorbia anacampseros var. tmolea: An Endemic Species of Turkey against Aedes aegypti. Asian Journal of Chemistry, 29(11), 2488–2492. https://doi.org/10.14233/ajchem.2017.20813
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