Synthesis and Anesthetic Activity of Some Mannich Bases of p-Dimethylamino Benzylidene Acetanilide
Corresponding Author(s) : R. Kalirajan
rkrmani@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 7 (2008): Vol 20 Issue 7
Abstract
Some Mannich bases of p-dimethylamino benzylidine
acetanilide are synthesized. The synthesized compounds have
been characterized by IR and 1H NMR analysis. An attempt
to determine the hydrophobic parameter (partition coefficient)
is also established. All the test compounds have been screened
for their local anaesthetic activity by Sollmann method.
acetanilide are synthesized. The synthesized compounds have
been characterized by IR and 1H NMR analysis. An attempt
to determine the hydrophobic parameter (partition coefficient)
is also established. All the test compounds have been screened
for their local anaesthetic activity by Sollmann method.
Keywords
Acetanilide
Mannich base
Anaesthetic activity.
Kalirajan, R., Jubie, S., Gowramma, B., & Suresh, B. (2010). Synthesis and Anesthetic Activity of Some Mannich Bases of p-Dimethylamino Benzylidene Acetanilide. Asian Journal of Chemistry, 20(7), 5289–5292. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12946
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