Synthesis and Antimicrobial Studies of Some Mn(II) Macrocyclic Complexes

Abstract

Two new Mn(II) macrocyclic complexes the formulae M[DPODH](BF₄)₂ and M[DCODH](BF₄)₂ where M = Mn(II), [DPODH] = 2,6-diacetyl pyridine-2,2'-oxydiacetoyl dihydrazone, [DCODH] = 2,6-pyridine dicarbonyl dichloride- 2,2'-oxydiacetoyl dihydrazone, BF₄ = tetrafluoro borate have been synthesized. These complexes have been analyzed for elemental analysis, spectral investigation and magnetic measurements. These complexes have also been screened in vitro antimicrobially against specific bacteria Escherichia coli, Staphylococcus aureus and fungal strain Aspergillus niger and Candida albicans. The results of the biological studies have shown that the complexes are at least five to six times more active than the ligand fragments.