Isolation of Cystine from Human Hair, Characterization, Pharmacological Screening on Frog Heart Muscle and Hepatoprotective Activity in Mice
Corresponding Author(s) : Biplab De
biplab_32@yahoo.co.in
Asian Journal of Chemistry,
Vol. 20 No. 7 (2008): Vol 20 Issue 7
Abstract
Hairs are elastic keratinised threads which develop from the epidermis and extend downwards into the subcutaneous tissue. Keratin is made from 16 amino acids. The most abundant of these amino acids is cystine, which was isolated by a new method and compared with the reference standard obtained from reported method. The crude extract was physicochemically characterized and pH adjusted to 7.4 for observation of its effect on frog heart muscle and for hepatoprotective activity in mice. Extract showed positive inotropic action and the ability to protect hepatotoxicity.
Keywords
Human hair
Cystine
Hepatoprotective
Heart muscle
De, B., Rudra Pal, M., Ranjan Bhattacharjee, P., Pal (Datta), S., Bhaumik, P., Behari Goswami, B., & Kumar Das, A. (2010). Isolation of Cystine from Human Hair, Characterization, Pharmacological Screening on Frog Heart Muscle and Hepatoprotective Activity in Mice. Asian Journal of Chemistry, 20(7), 5483–5488. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12883
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