Synthesis of A New Series of Bioactive Benzimidazoloylthiazoles

Abstract

The presence of thiazole ring in a compound is found to exhibit a wide variety of biological activity. In this synthetic method two versatile [4+1] synthetic strategies are demonstrated. 14 Densely functionalized ketothiazoles synthesized and the structure of these new compounds established spectroscopically using spectroscopic techniques. All the keto-thiazoles screened for antibacterial activity, out of which ten are found to be active against Bacillus subtilis.