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Vol. 20 No. 5 (2008): Vol 20 Issue 5

Antibacterial Activity of New [(2-Hydroxypropyl)-n-oximino]pyridines

NEJDET SEN
Department of Chemistry, Faculty of Science and Arts Selcuk University, 42079 Selcuklu, Konya, Turkey
YAKUP KAR
Department of Chemistry, Faculty of Science and Arts Selcuk University, 42079 Selcuklu, Konya, Turkey
SULTAN KURBANOV
Department of Chemistry, Faculty of Science and Arts Selcuk University, 42079 Selcuklu, Konya, Turkey
ARZU UYANIK
Department of Chemistry, Faculty of Science and Arts Selcuk University, 42079 Selcuklu, Konya, Turkey

Corresponding Author(s) : NEJDET SEN

nsen@selcuk.edu.tr

Asian Journal of Chemistry, Vol. 20 No. 5 (2008): Vol 20 Issue 5

Abstract

The synthesized [(2-hydroxypropyl)-n-oximino]pyridine derivatives has been tested against the pathogenic four Grampositive bacteria Bacillus cereus (ATCC 11778), Staphylococcus aureus (ATCC 6538), Sarcina lutea (ATCC 9341) and Streptococs mutans (UCTC 10499) and three Gram-negative bacteria Salmonella typhimurium (1,4,5,12:;:1,2), Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (ATCC 29998). Generally, all synthesized compounds (IVa-c) showed strong activity compared to antibiotic drug (cefalexin). However, among this compounds (IVa) showed excellent activity against Bacillus cereus (ATCC 11778), Sarcina lutea (ATCC 9341), Salmonella typhimurium (1,4,5,12:;:1,2) and Escherichia coli (ATCC 29998) compared to cefalexin.

Keywords

Pyridinecarbaldehyde oximes Antibacterial activity Gram-positive bacteria Gram-negative bacteria
SEN, N., KAR, Y., KURBANOV, S., & UYANIK, A. (2010). Antibacterial Activity of New [(2-Hydroxypropyl)-n-oximino]pyridines. Asian Journal of Chemistry, 20(5), 3949–3953. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12758
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