Nitric Oxide Synthase Activity on Erythrocyte of The Rabbits Which Implanted Composite Resin Filling Materials into Connective Tissue

Abstract

There have been considerable developments regarding the esthetic restorative material. Especially amalgam is replaced by the composites. Amalgam is not esthetic and has bad effects due to the presence of silver. This increases the use of composites and lead to the development of the new kinds. The aims of present study were to assess the alterations in nitric oxide synthase activity in erythrocytes of rabbits. Nitric oxide synthase activities were measured in all groups. Erythrocyte nitric oxide synthase activities were significantly increased in both the first day values and the seven compared to the baseline values. Reactive nitrogen species may play an important role in the cells and tissue damage due to composite resin-generated oxidative stress.