Synthesis and Antimicrobial Evaluation of Potent 6H-2-Amino-4,6-diaryl-1,3-thiazines

G. BASKAR; M. GOPALAKRISHNAN; J. WINFRED JABARAJ

Issue

Vol. 20 No. 4 (2008): Vol 20 Issue 4

Issue Published : January 19, 2008

Synthesis and Antimicrobial Evaluation of Potent 6H-2-Amino-4,6-diaryl-1,3-thiazines

G. BASKAR

Department of Chemistry, Annamalai University, Annamalai Nagar-608 002, India

M. GOPALAKRISHNAN

Department of Chemistry, Annamalai University, Annamalai Nagar-608 002, India

J. WINFRED JABARAJ

Department of Chemistry, Annamalai University, Annamalai Nagar-608 002, India

Corresponding Author(s) : G. BASKAR

drgbaskarg@yahoo.co.in

Asian Journal of Chemistry, Vol. 20 No. 4 (2008): Vol 20 Issue 4
Article Published : March 30, 2010

Abstract

In a ethanolic solution of 3′,5′-dichloro-2′-fluorochalcone (1a) and thiourea (2) when refluxed with aq. KOH for 5 h 6H-2-amino-4,6-diaryl-1,3-thiazines is formed. Likewise the chalcones 1b, 1c and 1d give the respective thiazines 5b, 5c and 5d. The products are analyzed by ¹H and ¹³C NMR spectra. The products are tested for antibacterial and antifungal activity.

Keywords

Antibacterial Antifungal 6H-2-Amino-4,6-diaryl-1,3-thiazines

BASKAR, G., GOPALAKRISHNAN, M., & WINFRED JABARAJ, J. (2010). Synthesis and Antimicrobial Evaluation of Potent 6H-2-Amino-4,6-diaryl-1,3-thiazines. Asian Journal of Chemistry, 20(4), 2802–2808. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12712

Issue

Vol. 20 No. 4 (2008): Vol 20 Issue 4

Synthesis and Antimicrobial Evaluation of Potent 6H-2-Amino-4,6-diaryl-1,3-thiazines

Corresponding Author(s) : G. BASKAR

Abstract

Keywords

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