Synthesis and Antimicrobial Activity of Tri-Substituted 1,6-Dihydropyrimidines
Corresponding Author(s) : B. RAMESH
rambha_vin@yahoo.com
Asian Journal of Chemistry,
Vol. 20 No. 4 (2008): Vol 20 Issue 4
Abstract
A series of substituted 1,6-dihydropyrimidines compounds have been synthesized by the reaction of ethylcyanoacetate, thiourea and substituted aldehydes in the presence of potassium carbonate and ethanol. Reactions have been carried out by conventional and microwave methods. The synthesized compounds are screened for their antibacterial and antifungal activity against Staphylococcus aureus, Escherichia coli and Candida albicans, Aspergillus flavus, respectively.
Keywords
Microwave
Antibacterial activity
1,6-Dihydropyrimidines
Synthesis
RAMESH, B., BHARATHI, D., BASAVARAJ, H., & JAYADEVAIAH, K. (2010). Synthesis and Antimicrobial Activity of Tri-Substituted 1,6-Dihydropyrimidines. Asian Journal of Chemistry, 20(4), 2591–2596. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/12607
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