Studies on the Complexes of Cu(II), Ni(II), Co(II), Mn(II), Zn(II), Cd(II) with the Isonicotinoylhydrazone-3-aldehydeindole

Abstract

Complexes of Cu(II), Ni(II), Co(II), Mn(II), Zn(II), Cd(II) have been synthetized with the aroylhydrazone ligand (INHAI) formed by condensation of the isonicotinoylhydrazine with 3-aldehydeindole. The complexes have been characterized by analytical data, IR, UV-Vis, NMR spectra, magnetic susceptibility, thermal analysis and for the Cu(II) complex by ESR spectrum. The biological activity of these complexes have been investigated for the bacterias Staphylococcus aureus, Escherichia coli and Proteus vulgaris. The INHAI ligand is coordinated bidentate by the oxygen amide C=O and the azomethine nitrogen in the complexes of Cu(II), Ni(II), Co(II) and monodentate by the nitrogen of the pyridinic ring in the complexes of Mn(II), Zn(II), Cd(II).