Spectral Measurements and Qualitative Analysis of Ceftriaxone and Cefotaxime

Abstract

The infrared, Raman and UV-visible spectroscopic measurements are employed for the qualitative analysis of antibiotic drugs viz., ceftriaxone and cefotaxime. The drugs chosen are from the family of cephalosporins, which are antibactericidal in nature. The different functional groups present in the compounds are identified and assigned satisfactorily using the FTIR and FT Raman spectra. UV-visible spectral investigation has been carried out to study the light absorption activity of the drugs at various environmental exposures like infrared radiation and sunlight. Further, the interaction of the drugs with some trace-elemental constituents such as calcium, magnesium, iron and lead has also been analyzed by employing UV-Visible spectral measurements.