Dimethyl Sulphoxide-Acetic Anhydride: An Excellent Source of Formaldehyde and Thiomethanol

Abstract

The reaction between DMSO and Ac₂O at water bath temperature yield formaldehyde and thiomethanol when exposed to this modified reagent. β-diketone and β-naphthol react with formaldehyde to give corresponding methylene-bis-derivatives and thiomethanol acting as Micheal donor reacts with compound (3Z)-3-(2-hydroxybenzylidine)-2H-chromene- 2,4(3H)-dione (7) to give an adduct 4-hydroxy-3[(2-hydroxyphenyl)( methylthiomethyl)]-2H-chromene-2-one (9) exposure of 7 to thiophenol give 4-hydroxy-3-[(2-hydroxyphenyl) (phenylthiomethyl)]-2H-chromen-2-one (10).