Synthesis and Antifungal Investigation of Co(II), Ni(II) Complexes with Nitrogen, Oxygen and Sulphur Donor Ligands

Abstract

Mixed ligand complexes of the type [M(LH₂)B₂] where M = Co(II) and Ni(II), L = 1-hydroxy-10-mercapto-1,2:5,6:9,10-tribenzo-3,7-diaza- 1,3,5,7,9-decapentene (LH₂), B = water, ammonia, phenyl isocyanide, quinoline, pyridine and α, β and γ-picolines. The ligand as well as metal complexes were characterized by physico-chemical technique. On the basis of above observations the geometry of the complexes were proposed to be octahedral. The LH₂ behaves as binegative tetradentate ligand. The remaining coordination sites are satisfied by neutral molecules. The ligand as well as metal complexes were screened for their antifungal activity.