Differential Scanning Calorimetry Studies of Solid Dispersion of Indometeocin Using Mixed Carriers

Abstract

Differential scanning calorimetry study was carried out to investigate the effect of temperature on physical mixture and solid dispersion of indomethacin. Various samples of indomethacin were analyzed at a heating rate of 40 per min using air as medium. Sharp thaw points of pure indomethacin and that of mixtures were determined for comparative study of drug-carrier interactions.