Synthesis, Characterization and Antimicrobial Activity of Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) Complexes of Schiff Bases Derived From 2-Amino-4(4'-methylphenyl)- thiazole and Substituted 4-Acetyl-1-phenyl-3-methyl-2-pyrazolin-5-ones

Abstract

2-Amino-4(4'-methylphenyl)-thiazole condensed with substituted 4-acetyl-1-phenyl-3-methyl- 2-pyrazolin-5-ones to form Schiff base. These Schiff bases from complexes of type ML₂·2H₂O (M = Mn, Fe, Co, Ni and Cu). Elemental analysis, magnetic susceptibility, electrical conductance, reflectance and infrared spectral data suggested octahedral structure for the complexes. All the compounds were tested for their antibacterial activity. The result indicates that the growth of the tested organism was inhibited by most of the compounds. These Schiff bases are characterized by elemental analysis, mass spectra, ¹H NMR spectra, ¹³C NMR spectra and FT-IR spectra.