Copyright (c) 2017 AJC
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Chemical Constituents of Kosteletzkya batacensis (Blanco) Fern.-Vill.
Corresponding Author(s) : Consolacion Y. Ragasa
Asian Journal of Chemistry,
Vol. 29 No. 9 (2017): Vol 29 Issue 9
Abstract
Chemical investigation of the dichloromethane extracts of Kosteletzkya batacensis (Blanco) Fern.-Vill., an endemic Philippine plant, has led to the isolation of b-sitosteryl-3b-glucopyranoside-6'-O-fatty acid esters (1), phytyl fatty acid esters (2), squalene (3) and chlorophyll-a (4) from the leaves; squalene (3), chlorophyll-a (4), a mixture of b-sitosterol (5a) and stigmasterol (5b) in a 2:1 ratio and long chain hydrocarbons (6) from the stems. The structures of compounds 1-6 were identified by comparison of their NMR data with literature data.
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References
J. van Borssum-Waalkes, Blumea, 14, 1 (1966).
Malvaceae–Co’s Digital Flora of the Philippines; www.philippineplants.org/Families/Malvaceae.html.
P.-W. Tsai, K.A. De Castro-Cruz, C.-C. Shen, C.-T. Chiou and C.Y. Ragasa, Pharm. Chem. J., 46, 225 (2012); https://doi.org/10.1007/s11094-012-0767-3.
C.Y. Ragasa, J.L. Caro, L.G. Lirio and C.-C. Shen, Res. J. Pharm. Biol. Chem. Sci., 5, 344 (2014).
C.Y. Ragasa, M.C.S. Tan, D.R. Fortin and C.-C. Shen, J. Appl. Pharm. Sci., 5, 062 (2015); https://doi.org/10.7324/JAPS.2015.50912.
C.Y. Ragasa and J. de Jesus, Res. J. Pharm. Biol. Chem. Sci., 5, 701 (2014).
C.Y. Ragasa, G.S. Lorena, E.H. Mandia, D.D. Raga and C.-C. Shen, Am. J. Essent. Oils Nat. Prod., 1, 7 (2013).
V.D. Ebajo Jr., R. Brkljaèa, S. Urban and C.Y. Ragasa, J. Appl. Pharm. Sci., 5, 69 (2015).
A.T. Nguyen, H. Malonne, P. Duez, R. Vanhaelen-Fastre, M. Vanhaelen and J. Fontaine, Fitoterapia, 75, 500 (2004); https://doi.org/10.1016/j.fitote.2004.03.009.
N.Y. Yoon, B.S. Min, H.K. Lee, J.C. Park and J.S. Choi, Arch. Pharm. Res., 28, 892 (2005); https://doi.org/10.1007/BF02973873.
C.V. Rao, H.L.N. Mark and R.S. Reddy, Carcinogenesis, 19, 287 (1998); https://doi.org/10.1093/carcin/19.2.287.
K.H.S. Farvin, R. Anandan, S.H.S. Kumar, K.S. Shiny, S. Mathew, T.V. Sankar and P.G.V. Nair, J. Med. Food, 9, 531 (2006); https://doi.org/10.1089/jmf.2006.9.531.
R. Loganathan, K.R. Selvaduray, K. Nesaretnam and A. Radhakrisnan, J. Oil Palm Res., 25, 208 (2013).
K.N. Desai, H. Wei and C.A. Lamartiniere, Cancer Lett., 101, 93 (1996); https://doi.org/10.1016/0304-3835(96)04122-5.
A.L. Ronco and E. De Stéfani, Funct. Food Health Dis., 3, 462 (2013).
B.J. Edwards, Physiotherapy, 40, 177 (1954).
J.C. Kephart, Econ. Bot., 9, 3 (1955); https://doi.org/10.1007/BF02984956.
D.C. Larato and F.R. Pfao, Dent. J., 36, 291 (1970).
R. Tawashi, M. Cousineau and M. Sharkawi, Invest. Urol., 18, 90 (1980).
E.D. Sternberg, D. Dolphin and C. Bruckner, Tetrahedron, 54, 4151 (1998); https://doi.org/10.1016/S0040-4020(98)00015-5.
W.L. Nourse, R.M. Parkhurst, W.A. Skinner and R.T. Jordan, Biochem. Biophys. Res. Commun., 151, 506 (1988); https://doi.org/10.1016/0006-291X(88)90622-5.
B.W. Henderson, D.A. Bellnier, W.R. Greco, A. Sharma, R.K. Pandry and L.A. Vaughan, Cancer Res., 57, 4000 (1997).
P.A. Egner, A. Munoz and T.W. Kensler, Mutat. Res., 523-524, 209 (2003); https://doi.org/10.1016/S0027-5107(02)00337-8.
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M.G. Ferruzzi and J. Blakeslee, Nutr. Res., 27, 1 (2007); https://doi.org/10.1016/j.nutres.2006.12.003.
A.B. Awad, M. Chinnam, C.S. Fink and P.G. Bradford, Phytomedicine, 14, 747 (2007); https://doi.org/10.1016/j.phymed.2007.01.003.
G.K. Jayaprakasha, K.K. Mandadi, S.M. Poulose, Y. Jadegoud, G.A. Nagana Gowda and B.S. Patil, Bioorg. Med. Chem., 15, 4923 (2007); https://doi.org/10.1016/j.bmc.2007.04.044.
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A.K. Batta, G. Xu, A. Honda, T. Miyazaki and G. Salen, Metabolism, 55, 292 (2006); https://doi.org/10.1016/j.metabol.2005.08.024.
M.A. Gómez, M.D. García and M.T. Sáenz, Phytother. Res., 15, 633 (2001); https://doi.org/10.1002/ptr.837.
Y. Kasahara, K. Kumaki, S. Katagiri, K. Yasukawa, S. Yamanouchi, M. Takido, T. Akihisa and T. Tamura, Phytother. Res., 8, 327 (1994); https://doi.org/10.1002/ptr.2650080603.
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M.D. García, M.T. Sáenz, M.A. Gómez and M.A. Fernández, Phytother. Res., 13, 78 (1999); https://doi.org/10.1002/(SICI)1099-1573(199902)13:1<78::AIDPTR384>3.0.CO;2-F.
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