Syntheses of Biologically Active 1-(Substituted aminomethyl)- 3-(2'-naphthoxyacetylhydrazono)indolin-2-ones
Corresponding Author(s) : Freddy H. Havaldar
drfreddy_11@yahoo.co.in
Asian Journal of Chemistry,
Vol. 22 No. 9 (2010): Vol 22 Issue 9
Abstract
2-Naphthoxyacetic acid hydrazide (1) was condensed with indole-2,3-dione in ethanol to yield 3-(2'-naphthoxyacetylhydrazono)indolin-2-one (2) which on aminomethylation with formaldehyde and different amines furnished 1-(substituted aminomethyl)-3-(2'-naphthoxyacetyl hydrazono)indolin-2-ones. The structures of the newly synthesized compounds have been established by analytical and spectral methods. These compounds have shown promising biological activity.
Keywords
Synthesis
Indolin-2-ones
Antibacterial and Antifungal activity
H. Havaldar, F., & K. Vasaikar, P. (2010). Syntheses of Biologically Active 1-(Substituted aminomethyl)- 3-(2’-naphthoxyacetylhydrazono)indolin-2-ones. Asian Journal of Chemistry, 22(9), 6677–6680. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11897
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