Synthesis, Characterization and Pharmacological Evaluation of Some Novel 3,6-Dinitrocarbazole Derivatives

Abstract

N-Mannich bases of newly synthesized carbazole compounds were synthesized from carbazole by reacting with series of aldehydes i.e., formaldehyde and acetaldehyde and the various secondary amines. Synthesized compounds were characterized by spectral studies and evaluated for antibacterial activities by cup and plate method. The statistical analysis was done by students "t" test and the values were expressed as mean ± SEM.