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Vol. 22 No. 8 (2010): Vol 22 Issue 8

Inhibitory Effects of Rifampicin On A Briggs-Rauscher Oscillating System

Gang Hu
Department of Chemistry, Anhui University, Hefei, Anhui 230039, P.R. China
Ling Zhu
Department of Chemistry, Anhui University, Hefei, Anhui 230039, P.R. China
Mi-Mi Guo
Department of Chemistry, Anhui University, Hefei, Anhui 230039, P.R. China
Hai-Yan Liu
Department of Chemistry, Anhui University, Hefei, Anhui 230039, P.R. China

Corresponding Author(s) : Gang Hu

hugky@21cn.com

Asian Journal of Chemistry, Vol. 22 No. 8 (2010): Vol 22 Issue 8

Abstract

Inhibitory effects of rifampicin on a novel Briggs-Rauscher oscillating system in which a macrocyclic nickel(II) complex ([NiL](ClO4)2) acts as the catalyst are studied. The ligand L is 5,7,7,12,14,14-hexemethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene. The experimental results indicate that, in the rifampicin concentration range of 2.6 to 22.5 μM, injection of rifampicin caused temporal ceasing of oscillations and then the oscillator resumed oscillations with obvious changes both in oscillation period and oscillating cycles. A mechanism on the effects of rifampicin is proposed based on Model NF.

Keywords

Inhibitory effects Briggs-Rauscher oscillation Macro-cyclic nickel(II) complex Rifampicin
Hu, G., Zhu, L., Guo, M.-M., & Liu, H.-Y. (2010). Inhibitory Effects of Rifampicin On A Briggs-Rauscher Oscillating System. Asian Journal of Chemistry, 22(8), 6393–6396. Retrieved from https://asianpubs.org/index.php/ajchem/article/view/11832
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