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Vol. 22 No. 8 (2010): Vol 22 Issue 8

A New Daphne Diterpenoids from Daphne acutiloba Rehd.

Yi-Ran Xu
Department of Chemistry, Yuxi Teacher's College, Yuxi-653100, P.R. China
Yin-Ke Li
Department of Chemistry, Yuxi Teacher's College, Yuxi-653100, P.R. China
Jing-Li Cao
School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming-650031, P.R. China E-mail: huqiufena@yahoo.com.cn †Department of Chemistry, Yuxi Teacher's College, Yuxi-653100, P.R. China. ‡Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming-650106, P.R. China.
Xin Zhang
Department of Chemistry, Yuxi Teacher's College, Yuxi-653100, P.R. China
Guang-Yu Yang
Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Acedemy of Tobacco Science, Kunming-650106, P.R. China
Qiu-fen Hu
School of Chemistry and Biotechnology, Yunnan Nationalities University, Kunming-650031, P.R. China ; Department of Chemistry, Yuxi Teacher's College, Yuxi-653100, P.R. China

Corresponding Author(s) : Qiu-fen Hu

huqiufena@yahoo.com.cn

Asian Journal of Chemistry, Vol. 22 No. 8 (2010): Vol 22 Issue 8

Abstract

A new daphne diterpenoid (daphnediterp A) was isolated from the leaf and steam of Daphne acutiloba Rehd. Its structure was determined by means of HRESIMS, extensive 1D and 2D NMR spectroscopic studies and chemical evidence. The anti HIV-1 activity was also evaluated and it shows an anti HIV-1 activity with a therapeutic index above 31.4.

Keywords

Daphne acutiloba Rehd daphne diterpenoid Anti-HIV-1 activity
(1)
Xu, Y.-R.; Li, Y.-K.; Cao, J.-L.; Zhang, X.; Yang, G.-Y.; Hu, Q.- fen. A New Daphne Diterpenoids from Daphne Acutiloba Rehd. ajc 2010, 22, 6371-6374.
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